Can't recall which thread it was posted in, I said I would research this. Much like the thoughts against backup QBs, I believe we have a tendency to remember bad beats vs our actual performance against rookie QBs. Games with just team, rookie wasn't the starter.
Here's the list. (I added sack #'s since amount of pressure is always discussed):
2021:
37-19 W over Trevor Lawrence - 23/33 273 1/1 28 rush yards 1 TD. 2 sacks.
27-24 OT L to Zach Wilson - 21/34 297 2/1. 1 Sack
2020:
31-20 L to Joe Burrow - 26/37 249 2/0. Did not sack
2019: None
2018:
13-12 L to Josh Allen - 10/19 82 0/1, 19 Rush yds 1 TD. 1 Sack
21-0 W (Baltimore) Lamar Jackson - 0/0. one 22 yard run.
2017:
57-14 L to Deshaun Watson - 25/34 283 4/1, 24 Rush yds 1 TD. 1 Sack
12-9 OT W over Deshone Kizer - 12/20 114 0/2. No sacks
2016:
28-26 W over Cody Kessler - 26/41 336 2/0. 6 Sacks
2015:
42-14 W over Jameis Winston - 16/33 210 2/2, 18 Rush yds. 4 sacks
2014:
16-14 over Blake Bortles - 32/46 336 1/1, 38 rush yds. 6 sacks.
21-13 L to Blake Bortles - 13/26 115 1/0, 50 rush yds. 4 sacks
45-21 L (Houston) Tom Savage - 2 kneel downs
2013:
38-13 W over Geno Smith - 23/34 289 1/2, 7 Rush yds. 5 Sacks
2012:
19-13 L to Andrew Luck - 26/38 297 1/1, 28 rush yds. 2 sacks.
27-23 L to Andrew Luck - 16/34 196 1/2. 4 sacks.
2011:
30-3 W over Cam Newton - 23/40 212 0/1, 55 rush yds. 5 sacks.
23-17 W over Blaine Gabbert - 21/42 198 0/1. 1 sack.
24-17 L to Andy Dalton - 22/39 217 3/0. 1 sack
23-22 W (Houston) TJ Yates - 4/4 47. 1 sack.
2010: None
2009:
24-17 L to Mark Sanchez - 17/30 171 2/1, 10 rush yds 1 TD. 3 sacks.
27-24 L (Miami) Pat White - 4 rush yards
47-7 W over Keith Null - 28/44 165 1/5. 1 sack.
2008:
13-10 W over Joe Flacco - 18/27 153 0/2. Not sacked.
2007: None
2006:
40-7 L (San Diego) Charlie Whitehurst - 14 rush yds 1 TD.
2005: None
2004:
51-24 L (Colts) Jim Sorgi - 0/1 3 kneel downs
19-17 L to Craig Krenzel - 10/28 116 0/2. 5 sacks
2003:
30-17 W over Byron Leftwich - 15/27 158 1/2. 2 sacks.
10-3 W over Byron Leftwich - 15/31 151 0/2. 1 sack
2002:
17-10 W over David Carr - 19/34 182 1/2. 4 sacks
13-3 W over David Carr - 21/40 214 0/1. 3 sacks
31-14 L to Patrick Ramsey - 20/34 268 2/0. 1 sack
23-14 W (Jaguars) David Garrard - 4/7 53 0/2, 71 rush yds 2 TD. 3 sacks
28-10 W (Jaguars) David Garrard - 6/13 43 1/0, 26 rush yds. 1 sack.
2001: None
2000:
24-10 W (Browns) Spurgeon Wynn - 0/0, 3 rush yds. 1 sack.
1999:
26-9 W over Tim Couch - 12/24 134 1/0, 40 rush yds. 7 sacks.
33-21 W over Tim Couch - 19/35 262 2/0, 29 rush yds 1 TD. 7 sacks.
36-35 W (Bengals) Akili Smith - 1/2 11.
Titans record against rookie QB - 17-11 - 73 sacks in those games, 2.5 sacks/game.
(23-14 in which a rookie "played")
2 - 300 yds QB (both w/ 336 exactly), both Titans victory
2 - more than 2 TD passes, both L. (Watson, Dalton)
total TD: INT - 32/35 with 6 rush TD.
Feel free to point out any errors.
Here's the list. (I added sack #'s since amount of pressure is always discussed):
2021:
37-19 W over Trevor Lawrence - 23/33 273 1/1 28 rush yards 1 TD. 2 sacks.
27-24 OT L to Zach Wilson - 21/34 297 2/1. 1 Sack
2020:
31-20 L to Joe Burrow - 26/37 249 2/0. Did not sack
2019: None
2018:
13-12 L to Josh Allen - 10/19 82 0/1, 19 Rush yds 1 TD. 1 Sack
21-0 W (Baltimore) Lamar Jackson - 0/0. one 22 yard run.
2017:
57-14 L to Deshaun Watson - 25/34 283 4/1, 24 Rush yds 1 TD. 1 Sack
12-9 OT W over Deshone Kizer - 12/20 114 0/2. No sacks
2016:
28-26 W over Cody Kessler - 26/41 336 2/0. 6 Sacks
2015:
42-14 W over Jameis Winston - 16/33 210 2/2, 18 Rush yds. 4 sacks
2014:
16-14 over Blake Bortles - 32/46 336 1/1, 38 rush yds. 6 sacks.
21-13 L to Blake Bortles - 13/26 115 1/0, 50 rush yds. 4 sacks
45-21 L (Houston) Tom Savage - 2 kneel downs
2013:
38-13 W over Geno Smith - 23/34 289 1/2, 7 Rush yds. 5 Sacks
2012:
19-13 L to Andrew Luck - 26/38 297 1/1, 28 rush yds. 2 sacks.
27-23 L to Andrew Luck - 16/34 196 1/2. 4 sacks.
2011:
30-3 W over Cam Newton - 23/40 212 0/1, 55 rush yds. 5 sacks.
23-17 W over Blaine Gabbert - 21/42 198 0/1. 1 sack.
24-17 L to Andy Dalton - 22/39 217 3/0. 1 sack
23-22 W (Houston) TJ Yates - 4/4 47. 1 sack.
2010: None
2009:
24-17 L to Mark Sanchez - 17/30 171 2/1, 10 rush yds 1 TD. 3 sacks.
27-24 L (Miami) Pat White - 4 rush yards
47-7 W over Keith Null - 28/44 165 1/5. 1 sack.
2008:
13-10 W over Joe Flacco - 18/27 153 0/2. Not sacked.
2007: None
2006:
40-7 L (San Diego) Charlie Whitehurst - 14 rush yds 1 TD.
2005: None
2004:
51-24 L (Colts) Jim Sorgi - 0/1 3 kneel downs
19-17 L to Craig Krenzel - 10/28 116 0/2. 5 sacks
2003:
30-17 W over Byron Leftwich - 15/27 158 1/2. 2 sacks.
10-3 W over Byron Leftwich - 15/31 151 0/2. 1 sack
2002:
17-10 W over David Carr - 19/34 182 1/2. 4 sacks
13-3 W over David Carr - 21/40 214 0/1. 3 sacks
31-14 L to Patrick Ramsey - 20/34 268 2/0. 1 sack
23-14 W (Jaguars) David Garrard - 4/7 53 0/2, 71 rush yds 2 TD. 3 sacks
28-10 W (Jaguars) David Garrard - 6/13 43 1/0, 26 rush yds. 1 sack.
2001: None
2000:
24-10 W (Browns) Spurgeon Wynn - 0/0, 3 rush yds. 1 sack.
1999:
26-9 W over Tim Couch - 12/24 134 1/0, 40 rush yds. 7 sacks.
33-21 W over Tim Couch - 19/35 262 2/0, 29 rush yds 1 TD. 7 sacks.
36-35 W (Bengals) Akili Smith - 1/2 11.
Titans record against rookie QB - 17-11 - 73 sacks in those games, 2.5 sacks/game.
(23-14 in which a rookie "played")
2 - 300 yds QB (both w/ 336 exactly), both Titans victory
2 - more than 2 TD passes, both L. (Watson, Dalton)
total TD: INT - 32/35 with 6 rush TD.
Feel free to point out any errors.